CASQ2 antibody

Catalog No. ABIN7259392

This Rabbit Polyclonal antibody specifically detects CASQ2 in IHC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for CASQ2 antibody (ABIN7259392)

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASQ2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CASQ2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CASQ2 (NP_001223.2).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Alternative Name: CASQ2

Background: The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Gene ID: 845

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity