TPT1 antibody (AA 85-172) (Cy3)

Catalog No. ABIN701083

This Rabbit Polyclonal antibody specifically detects TPT1 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for TPT1 antibody (AA 85-172) (Cy3) (ABIN701083)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPT1 antibody is conjugated to Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TPT1 Antibody (Cy3)

Binding Specificity: AA 85-172

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCTP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TCTP

Background:

Synonyms: FLJ27337, Fortilin, Histamine releasing factor, Histamine-releasing factor, HRF, Immunoglobulin E-dependent, p02, p23, TCTP, TCTP_HUMAN, TPT1, Translationally controlled tumor protein, Translationally-controlled tumor protein, Tumor protein translationally controlled 1, tumor protein translationally-controlled 1, tumor protein, translationally-controlled 1.

Background: TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).

Gene ID: 7178

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling