HLA-E antibody
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- Target See all HLA-E Antibodies
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This HLA-E antibody is un-conjugated
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Application
- Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP)
- Purpose
- Anti-HLA-E Purified
- Specificity
- The mouse monoclonal antibody 3D12 (also known as 3D12HLA-E) recognizes native extracellular part of HLA-E, an ubiquitously expressed non-classical MHC class I molecule, as well as free HLA-E.
- Purification
- Purified by protein-A affinity chromatography.
- Immunogen
- recombinant human HLA-E
- Clone
- 3D12
- Isotype
- IgG1
- Top Product
- Discover our top product HLA-E Primary Antibody
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anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) (AA 251-358) antibody
HLA-E Reactivity: Human WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) (AA 1-358) antibodyHLA-E Reactivity: Human WB, FACS Host: Mouse Polyclonal unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) (AA 22-358) antibodyHLA-E Reactivity: Human WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) antibodyHLA-E Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) (AA 108-135) antibodyHLA-E Reactivity: Human WB Host: Rabbit Polyclonal RB22054 unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) antibodyHLA-E Reactivity: Human, Primate WB, IHC, IHC (p) Host: Mouse Monoclonal MEM-E-02 unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) (AA 1-358) antibodyHLA-E Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) antibody (PE)HLA-E Reactivity: Human FACS Host: Mouse Monoclonal 3D12 PE
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) antibody (APC)HLA-E Reactivity: Human FACS Host: Mouse Monoclonal 3D12 APC
anti-HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E) (AA 1-100) antibodyHLA-E Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
- Alternative Name
- HLA-E (HLA-E Products)
- Background
- Major histocompatibility complex, class I, E,HLA-E (human leukocyte antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells).,HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E
- Gene ID
- 3133
- UniProt
- P13747
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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