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VCAM1 antibody (PE)

VCAM1 Reactivity: Mouse FACS Host: Rat Monoclonal 429 (MVCAM-A) PE
Catalog No. ABIN7014005
  • Target See all VCAM1 Antibodies
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Reactivity
    • 136
    • 95
    • 55
    • 25
    • 15
    • 8
    • 8
    • 4
    • 3
    • 1
    Mouse
    Host
    • 96
    • 72
    • 32
    • 5
    • 1
    • 1
    Rat
    Clonality
    • 114
    • 91
    • 1
    Monoclonal
    Conjugate
    • 94
    • 27
    • 24
    • 11
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VCAM1 antibody is conjugated to PE
    Application
    • 115
    • 96
    • 53
    • 42
    • 35
    • 32
    • 27
    • 26
    • 21
    • 16
    • 16
    • 13
    • 8
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    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Murine preadipose cell line PA6
    Clone
    429 (MVCAM-A)
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Alternative Name
    CD106 (VCAM1 Products)
    Synonyms
    CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
    Background
    Vascular cell adhesion molecule 1,CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.,Vcam-1
    Gene ID
    22329
    UniProt
    Q3UPN1
    Pathways
    Carbohydrate Homeostasis
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