Caspase 7 antibody (AA 101-200) (HRP)

Catalog No. ABIN702349

This Rabbit Polyclonal antibody specifically detects Caspase 7 in WB, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Caspase 7 antibody (AA 101-200) (HRP) (ABIN702349)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 7 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Caspase 7 Antibody (HRP)

Binding Specificity: AA 101-200

Purpose: Caspase-7 p20 Polyclonal Antibody, HRP Conjugated

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Caspase-7

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Alternative Name: Caspase-7

Background:

Synonyms: MCH3, CMH-1, LICE2, CASP-7, ICE-LAP3, Caspase-7, Apoptotic protease Mch-3, ICE-like apoptotic protease 3, CASP7

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

Gene ID: 840

UniProt: P55210

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity