Recombinant MMP14 antibody (AA 218-233)

Catalog No. ABIN7072294

This Mouse Monoclonal antibody specifically detects MMP14 in ELISA and BP. It exhibits reactivity toward Human.

Quick Overview for Recombinant MMP14 antibody (AA 218-233) (ABIN7072294)

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP14 antibody is un-conjugated

Application: ELISA, Blocking Peptide (BP)

Clone: LEM-2-15

Product Details anti-MMP14 Antibody

Binding Specificity: AA 218-233

Purpose: Anti-Membrane type 1 metalloprotease [LEM-2/15], Mouse IgG1, kappa

Specificity: This antibody binds to residues 218-233 of the V-B loop of MT1-MMP with a Kd of 2.32E10-9M.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: The cyclic peptide possessing the sequence of residues 218-233 of the V-B-loop of MT1-MMP.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody binds to residues 218-233 of the V-B loop of MT1-MMP which is a mediator of cell migration and is frequently involved in malignancy of tumours by promoting metastasis. The antibody acts as a non-competitive inhibitor of the receptor.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Alternative Name: Membrane type 1 metalloprotease

Background: MT1-MMP

Pathways: Autophagy