Recombinant TNFRSF8 antibody
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- Target See all TNFRSF8 Antibodies
- TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Chimeric
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Conjugate
- This TNFRSF8 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Activation (Act)
- Purpose
- Anti-CD30 [Ki-3], Rabbit IgG, kappa
- Specificity
- The antibody binds to CD30.
- Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
- Purification
- Protein A affinity purified
- Immunogen
- Human CD30.
- Clone
- Ki-3
- Isotype
- IgG kappa
- Top Product
- Discover our top product TNFRSF8 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 19-379) antibody
TNFRSF8 Reactivity: Human IHC, WB, IHC (p) Host: Mouse Monoclonal 18D3 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 19-379) antibodyTNFRSF8 Reactivity: Human IHC, WB, IHC (p) Host: Mouse Monoclonal 1C6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 3B10 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 19-379) antibodyTNFRSF8 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4D1C2 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 Reactivity: Human FACS, IHC (p) Host: Mouse Monoclonal MEM-268 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) (AA 131-230) antibodyTNFRSF8 Reactivity: Human, Pig FACS, WB, IHC (p), ELISA, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibody (APC)TNFRSF8 Reactivity: Human FACS Host: Mouse Monoclonal MEM-268 APC
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 Reactivity: Human IF, WB Host: Rabbit Monoclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8) antibodyTNFRSF8 Reactivity: Human FACS, WB, IHC (p), IP Host: Mouse Monoclonal Ber-H2 unconjugated
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- Application Notes
- The antibody binds specifically to CD30, a cell membrane protein which belongs to the tumour necrosis factor receptor family. Incubation of CD30 positive L540 cells with Ki-3 antibody weakly enhances release of soluble CD30 (in contrast to Ki-4, Ab00475). CD30 is expressed on activated lymphocytes, and binding by its ligands TRAF2 and TRAF5 results in the activation of NF-kappaB, thereby regulating gene expression. CD30 is also associated with Hodgkin Lymphoma, and its expression acts as a tumour marker. Targeting the CD30 antigen with specific monoclonal antibodies is a possible therapy for Hodgkin's lymphoma.
- Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
- Alternative Name
- CD30 (TNFRSF8 Products)
- Background
- TNFRSF8, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30
- UniProt
- P28908
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