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Recombinant TNFRSF8 antibody

TNFRSF8 Reactivity: Human FACS, IHC, IF, ELISA, Act Host: Mouse Monoclonal Ki-3 unconjugated Recombinant Antibody
Catalog No. ABIN7072329
  • Target See all TNFRSF8 Antibodies
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 148
    • 32
    • 19
    • 16
    Human
    Host
    • 92
    • 70
    • 14
    • 4
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 110
    • 71
    • 2
    Monoclonal
    Conjugate
    • 80
    • 15
    • 13
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF8 antibody is un-conjugated
    Application
    • 118
    • 56
    • 52
    • 46
    • 36
    • 27
    • 27
    • 26
    • 13
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Activation (Act)
    Purpose
    Anti-CD30 [Ki-3], Mouse IgG2b, kappa
    Specificity
    The antibody binds to CD30.
    Characteristics

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2b

    Purification
    Protein A affinity purified
    Immunogen
    Human CD30.
    Clone
    Ki-3
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product TNFRSF8 Primary Antibody
  • Application Notes
    The antibody binds specifically to CD30, a cell membrane protein which belongs to the tumour necrosis factor receptor family. Incubation of CD30 positive L540 cells with Ki-3 antibody weakly enhances release of soluble CD30 (in contrast to Ki-4, Ab00475). CD30 is expressed on activated lymphocytes, and binding by its ligands TRAF2 and TRAF5 results in the activation of NF-kappaB, thereby regulating gene expression. CD30 is also associated with Hodgkin Lymphoma, and its expression acts as a tumour marker. Targeting the CD30 antigen with specific monoclonal antibodies is a possible therapy for Hodgkin's lymphoma.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    TNFRSF8 (Tumor Necrosis Factor Receptor Superfamily, Member 8 (TNFRSF8))
    Alternative Name
    CD30 (TNFRSF8 Products)
    Background
    TNFRSF8, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30
    UniProt
    P28908
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