Recombinant CD131 antibody

Catalog No. ABIN7072454

Product Details anti-CD131 Antibody

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD131 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Blocking Peptide (BP), Crystallization (Crys), Functional Studies (Func)

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG

Purification: Purified antibody.

Immunogen: BALB/c mice were immunized intraperitonally with COS cells transfected DQP (Domain 4 of the common beta-chain) expression constructs. The immunizations were repeated 4 times at 2-week intervals. Four weeks after the final immunization, a mouse was boosted with COS transfectants intravenously. Three days later, splenocytes were harvested and fused with NS-1 myeloma cells. Hybridoma supernatants were screened on CHO DQP cells by flow cytometry, with untransfected CHO cells as a control. All antibodies were from single hybridoma clones as selected by a limiting dilution method. MoAbs were purified from ascites fluid or hybridoma supernatant by a protein A sepharose column.

Clone: BION-1

Isotype: IgG kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD131

Target: CD131 (CSF2RB) (Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))

Alternative Name: CD131 (CSF2RB Products)

Synonyms: Csf2rb1 antibody, CSF2RB antibody, cd131 antibody, cdw131 antibody, il3rb antibody, il5rb antibody, il-3rbc antibody, CD131 antibody, CDw131 antibody, IL3RB antibody, IL5RB antibody, SMDP5 antibody, AI848964 antibody, AIC2B antibody, Bc antibody, Csfgmrb antibody, Il3r antibody, Il3rb antibody, Il3rb1 antibody, Il5rb antibody, colony stimulating factor 2 receptor beta common subunit antibody, colony stimulating factor 2 receptor beta common subunit S homeolog antibody, cytokine receptor common subunit beta-like antibody, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) antibody, CSF2RB antibody, Csf2rb antibody, csf2rb.S antibody, CRCBL antibody, csf2rb antibody

Background: CSF2RB, CD131, IL3RB, IL-3R common beta subunit, IL5RB, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), SMDP5, Common Beta-Chain, CDw131, cytokine receptor common subunit beta, beta-c, CD131, Beta Common Chain

UniProt: P32927

Pathways: JAK-STAT Signaling