Recombinant IL2 Receptor beta antibody

Catalog No. ABIN7072574

The Rat Monoclonal anti-IL2 Receptor beta antibody is suitable to detect IL2 Receptor beta in samples from Mouse. It has been validated for FACS.

Quick Overview for Recombinant IL2 Receptor beta antibody (ABIN7072574)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL2 Receptor beta antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 5H4

Product Details anti-IL2 Receptor beta Antibody

Purpose: Anti-IL2R beta [5H4], Rat IgG2a, kappa

Specificity:

This antibody is specific for the murine interleukin-2 receptor beta chain.

Application Notes original Clone: This antibody has been used in flow cytometric analysis of IL-2R beta expression by thymocytes, lymph node cells and 3B4.15 T hybridoma cells (Ligons et al, 2012), as well as NK cells (He et al, 1996, Frenkel et al, 2016, Put et al, 2016, Elkabets et al, 2009).

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunising Lewis rats with transfected rat myeloma cell line YB2/0, expressing truncated murine IL-2R beta.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Rat

OriginalFormat: IgG2a

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Alternative Name: IL2R beta

Background: CD122, IL-2Rβ, IL-2 receptor subunit beta, Interleukin-2 receptor subunit beta, High affinity IL-2 receptor subunit beta, p70-75

UniProt: P16297

Pathways: JAK-STAT Signaling, Growth Factor Binding