Recombinant CD1a antibody

Catalog No. ABIN7072626

The Rabbit Chimeric anti-CD1a antibody (Clone CBT6) (ABIN7072626) specifically detects CD1a in FACS, IHC, ELISA and IP. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD1a antibody (ABIN7072626)

Target: CD1a

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD1a antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Clone: CBT6

Product Details anti-CD1a Antibody

Purpose: Anti-CD1a [CBT6], Rabbit IgG, kappa

Specificity:

The antibody is specific for the human CD1a protein.

Application Notes original Clone: The antibody can be used to inhibit Sag-induced proliferation of MHC class II thymocytes (Gregory. et al, 2000). It can increase intracellular calcium concentration in MHC class II thymocytes if used toghether with rabbit anti-mouse antibodies (Gregory. et al, 2000). This antibody is shown to be useful in flow cytometry (Gregory. et al, 2000). Immunofluorescence is a method for which this antibody can also be used (Brocks. et al, 2017). The antibody can be utilized in immunihistochemistry to seperate human cells from cells of other animals (Goan. et al, 2000). The antibody is also reccomended for use in ELISA and immunoprecipitation.

Characteristics: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with the human CD1a protein.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Mouse

OriginalFormat: IgG1

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD1a

Target: CD1a

Alternative Name: CD1a

Background: T6/Leu6, T-cell surface antigen T6/Leu-6, T6, Leu 6, hTa1 thymocyte antigen, FCB6, R4, hTa1 thymocyte antigen

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process