Recombinant PRMT5 antibody (AA 269-637)

Catalog No. ABIN7072696

This Rabbit Chimeric antibody specifically detects PRMT5 in ELISA, IF, ChIP and MS. It exhibits reactivity toward Human.

Quick Overview for Recombinant PRMT5 antibody (AA 269-637) (ABIN7072696)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This PRMT5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Mass Spectrometry (MS)

Clone: RAB-C136

Product Details anti-PRMT5 Antibody

Binding Specificity: AA 269-637

Purpose: Anti-PRMT5 [RAB-C136], Rabbit IgG, kappa

Specificity:

This antibody recognizes PRMT5 (Protein arginine N-methyltransferase 5). It binds to a folded domain, amino acids 269-637. PRMT5 is a arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA.

Application Notes original Clone: This antibody has been used and recommended for the following methods: ELISA, IF, IP-MS, ChIP.

Characteristics: This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing PRMT5 protein under non-denaturing conditions.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Human

OriginalFormat: Fab

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Alternative Name: PRMT5

Background: PRMT5, Protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog, SKB1 homolog, SKB1Hs, anti-PRMT5-RAB-C136, 48F3_10

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development