Recombinant SETD7 antibody (AA 2-366)

Catalog No. ABIN7072703

The Rabbit Chimeric anti-SETD7 antibody is suitable to detect SETD7 in samples from Human. It has been validated for ELISA, FACS, IF, IP, ChIP and MS.

Quick Overview for Recombinant SETD7 antibody (AA 2-366) (ABIN7072703)

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This SETD7 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Mass Spectrometry (MS)

Clone: RAB-C220

Product Details anti-SETD7 Antibody

Binding Specificity: AA 2-366

Purpose: Anti-SETD7 [RAB-C220], Rabbit IgG, kappa

Specificity:

This antibody recognizes SETD7 (Histone-lysine N-methyltransferase SETD7). It binds to a folded domain, amino acids 2-366. SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin.

Application Notes original Clone: This antibody has been used and recommended for the following methods: ELISA, IF, spiked IP, IP-MS, ChIP, FC.

Characteristics: This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing SETD7 protein under non-denaturing conditions.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Human

OriginalFormat: Fab

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for SETD7

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Alternative Name: SETD7

Background: SET7/9, Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, anti-SETD7-RAB-C220, 48H1_2

UniProt: Q8WTS6