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CRTC1 antibody

CRTC1 Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7073590
  • Target See all CRTC1 Antibodies
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Reactivity
    • 68
    • 36
    • 24
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 55
    • 13
    • 1
    Rabbit
    Clonality
    • 55
    • 14
    Polyclonal
    Conjugate
    • 32
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CRTC1 antibody is un-conjugated
    Application
    • 53
    • 25
    • 20
    • 13
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse TORC1
    Top Product
    Discover our top product CRTC1 Primary Antibody
  • Application Notes
    IHC/IF (M,R) 1:400-1:800
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Alternative Name
    TORC1 (CRTC1 Products)
    Synonyms
    MECT1 antibody, TORC-1 antibody, TORC1 antibody, WAMTP1 antibody, AI413414 antibody, Mect1 antibody, R74955 antibody, mKIAA0616 antibody, CRTC1 antibody, crtc1 antibody, fc68c05 antibody, pde4cb antibody, si:ch211-255d18.1 antibody, si:ch211-255d18.8 antibody, wu:fc68c05 antibody, CREB regulated transcription coactivator 1 antibody, CREB regulated transcription coactivator 1b antibody, CRTC1 antibody, Crtc1 antibody, crtc1 antibody, crtc1b antibody
    Background
    CRTC1, also named as MECT1, TORC1, and WAMTP1, belongs to the TORC family. It is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. CRTC1 acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. It enhances the interaction of CREB1 with TAF4. CRTC1 regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. It is a potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.
    Gene ID
    382056
    NCBI Accession
    NP_001004062
    UniProt
    Q68ED7
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