CRTC1 antibody (C-Term)

Catalog No. ABIN7448839

This Rabbit Polyclonal antibody specifically detects CRTC1 in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for CRTC1 antibody (C-Term) (ABIN7448839)

Target: CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRTC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CRTC1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-TORC1 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Zebrafish,Dog,Horse,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Nile tilapia,African elephant,Tasmanian devil,Japanese pufferfish,Chinese hamster,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Little brown bat,Three-spined stickleback,White-tufted-ear marmoset,Naked mole rat,Small-eared galago,Spotted green pufferfish

Purification: Affinity Purified

Immunogen: Between AA 600 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CRTC1

Target: CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))

Alternative Name: TORC1

Background: Background: TORC1 (transducer of regulated CREB activity 1) is part of a family of CREB (cAMP response element-binding protein) coactivators that also includes TORC2 and TORC3. These proteins function to activate CREB-dependent transcription in response to cAMP and calcium signaling pathways. The TORC family of proteins has been shown to regulate transcription of PGC-1 alpha, a regulator of mitochondrial genes.

Gene ID: 23373

NCBI Accession: NP_056136

UniProt: Q6UUV9