IP3 Receptor antibody

Catalog No. ABIN7074293

This Rabbit Polyclonal antibody specifically detects IP3 Receptor in WB, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for IP3 Receptor antibody (ABIN7074293)

Target: IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IP3 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IP3 Receptor Antibody

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human IP3 receptor

Application Details

Application Notes: WB (H) 1: 500-1: 1000, IHC/IF (M,R) 1:500-1:1500/1:750-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IP3 Receptor

Target: IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))

Alternative Name: IP3 receptor

Background: Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ITPR1 gene. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Molecular Weight: 313 kDa

Gene ID: 3708

NCBI Accession: NP_001093422

UniProt: Q14643

Pathways: Fc-epsilon Receptor Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma