IFIT5 antibody

Catalog No. ABIN7074334

The Rabbit Polyclonal anti-IFIT5 antibody (ABIN7074334) specifically detects IFIT5 in IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for IFIT5 antibody (ABIN7074334)

Target: IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIT5 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-IFIT5 Antibody

Cross-Reactivity: Mouse

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Human IFIT5

Application Details

Application Notes: IHC/IF (H,M) 1:300-1:1800

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IFIT5

Target: IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))

Alternative Name: IFIT5

Background: Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

Gene ID: 24138

NCBI Accession: NP_036552

UniProt: Q13325