IFIT5 antibody (AA 250-330)

Catalog No. ABIN7220816

This Rabbit Polyclonal antibody specifically detects IFIT5 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for IFIT5 antibody (AA 250-330) (ABIN7220816)

Target: IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFIT5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IFIT5 Antibody

Binding Specificity: AA 250-330

Purpose: Rabbit Anti-IFIT-5 Polyclonal Antibody

Specificity: IFIT-5 Polyclonal Antibody detects endogenous levels of IFIT-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human IFIT-5 at AA range: 250-330

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for IFIT5

Target: IFIT5 (Interferon-Induced Protein with Tetratricopeptide Repeats 5 (IFIT5))

Alternative Name: IFIT-5

Background: IFIT5, ISG58, RI58, Interferon-induced protein with tetratricopeptide repeats 5, IFIT-5, Interferon-induced 58 kDa protein, Retinoic acid- and interferon-inducible 58 kDa protein, P58IFIT5 (Interferon Induced Protein With Tetratricopeptide Repeats 5) is a Protein Coding gene. GO annotations related to this gene include poly(A) RNA binding and tRNA binding. An important paralog of this gene is IFIT1. nterferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2-O-methylation of the 5 cap and bear a 5-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

Molecular Weight: 50kD

Gene ID: 24138

UniProt: Q13325