KDM5A antibody

Catalog No. ABIN7074532

The Rabbit Polyclonal anti-KDM5A antibody (ABIN7074532) specifically detects KDM5A in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for KDM5A antibody (ABIN7074532)

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM5A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM5A Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse KDM5A

Application Details

Application Notes: WB (H,M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for KDM5A

Target: KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))

Alternative Name: KDM5A/Jarid1A/RBBP2

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molecular Weight: 192 kDa

Gene ID: 214899

NCBI Accession: NP_666109

UniProt: Q3UXZ9

Pathways: Chromatin Binding, Warburg Effect