NUDT5 antibody

Catalog No. ABIN7074929

This Rabbit Polyclonal antibody specifically detects NUDT5 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NUDT5 antibody (ABIN7074929)

Target: NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUDT5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NUDT5 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse NUDT5

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for NUDT5

Target: NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))

Alternative Name: NUDT5

Background: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.

Molecular Weight: 34 kDa

Gene ID: 53893

NCBI Accession: NP_058614

UniProt: Q9JKX6