SPZ1 antibody

Catalog No. ABIN7075701

The Rabbit Polyclonal anti-SPZ1 antibody is suitable to detect SPZ1 in samples from Mouse and Rat. It has been validated for WB.

Quick Overview for SPZ1 antibody (ABIN7075701)

Target: SPZ1 (Spermatogenic Leucine Zipper 1 (SPZ1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPZ1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SPZ1 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse SPZ1

Application Details

Application Notes: WB (M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SPZ1

Target: SPZ1 (Spermatogenic Leucine Zipper 1 (SPZ1))

Alternative Name: SPZ1

Background: Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.

Molecular Weight: 43 kDa

Gene ID: 79401

NCBI Accession: NP_084513

UniProt: Q99MY0

Pathways: MAPK Signaling