TOR1A antibody

Catalog No. ABIN7075942

The Rabbit Polyclonal anti-TOR1A antibody (ABIN7075942) specifically detects TOR1A in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TOR1A antibody (ABIN7075942)

Target: TOR1A (Torsin Family 1, Member A (Torsin A) (TOR1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TOR1A Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Torsin A

Application Details

Application Notes: WB (M,R) 1: 500-1: 1000, IHC/IF (H,R) 1:800-1:1600/1:1500-1:3000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TOR1A

Target: TOR1A (Torsin Family 1, Member A (Torsin A) (TOR1A))

Alternative Name: Torsin A/DYT1

Background: TOR1A (torsin A), also known as DYT1, is a member of the AAA family of adenosine triphosphatases (ATPases) that mediate chaperone and other functions involved in conformational modeling of proteins, protection from stress, and targeting of proteins to cellular organelles. TOR1A primarily localizes to the ER while exposure to oxidative stress causes the redistribution to cell surface protrusions. Mutations in gene encoding TOR1A cause the most severe form of hereditary dystonia, termed early onset, generalized dystonia.

Molecular Weight: 38 kDa

Gene ID: 30931

NCBI Accession: NP_659133

UniProt: Q9ER39

Pathways: SARS-CoV-2 Protein Interactome