UPK1A antibody
Quick Overview for UPK1A antibody (ABIN7076160)
Target
See all UPK1A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse Uroplakin Ia
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Application Notes
- WB (R) 1:300-1:600, IHC/IF (M,R) 1:2000-1:4000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- UPK1A (Uroplakin 1a (UPK1A))
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Alternative Name
- Uroplakin Ia
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Background
- Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention . Uroplakin-1a (UPK1A) belongs to the tetraspanin (TM4SF) family. UPK1A plays an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane.
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Molecular Weight
- 29 kDa
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Gene ID
- 109637
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NCBI Accession
- NP_081091
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UniProt
- Q9D132
Target
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