UPK1A antibody (C-Term)

Catalog No. ABIN653173

This Rabbit Polyclonal antibody specifically detects UPK1A in WB. It exhibits reactivity toward Human.

Quick Overview for UPK1A antibody (C-Term) (ABIN653173)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB23236

Product Details anti-UPK1A Antibody

Binding Specificity: AA 191-217, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UPK1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-217 amino acids from the C-terminal region of human UPK1A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: UPK1A

Background: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

Molecular Weight: 28879

Gene ID: 11045

NCBI Accession: NP_001268372, NP_008931

UniProt: O00322