CD4 antibody (FITC)

Catalog No. ABIN7076565

This anti-CD4 antibody is a Mouse Monoclonal antibody detecting CD4 in FACS. Suitable for Human, Rhesus Monkey and Cynomolgus.

Quick Overview for CD4 antibody (FITC) (ABIN7076565)

Target: CD4

Reactivity: Human, Rhesus Monkey, Cynomolgus

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Grade: GMP Grade (Analyte)

Clone: OKT4

Product Details anti-CD4 Antibody (FITC)

Purpose: CD4 FITC Antibody

Characteristics: CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding

Purification: Purified

Purity: >95 %

Immunogen: Human peripheral blood T lymphocytes

Isotype: IgG2b, kappa

Application Details

Application Notes: FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Gene ID: 920

NCBI Accession: NM_000616

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events