NGFR antibody (iFluor™647)
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- Target See all NGFR Antibodies
- NGFR (Nerve Growth Factor Receptor (NGFR))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NGFR antibody is conjugated to iFluor™647
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Application
- Flow Cytometry (FACS)
- Purpose
- CD271 iFluor647 Antibody
- Characteristics
- The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily. Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc. Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.
- Purification
- Purified
- Purity
- >95 %
- Grade
- GMP Grade
- Immunogen
- WM245 melanoma cells
- Clone
- ME20-4
- Isotype
- IgG1, kappa
- Top Product
- Discover our top product NGFR Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- 2-8°C, Conjugated antibodies should never be frozen.
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- Target
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Alternative Name
- CD271 (NGFR Products)
- Gene ID
- 4804
- UniProt
- P08138
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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