NGFR antibody (iFluor™647)
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- Target See all NGFR Antibodies
- NGFR (Nerve Growth Factor Receptor (NGFR))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This NGFR antibody is conjugated to iFluor™647
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Application
- Flow Cytometry (FACS)
- Characteristics
- The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily. Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc. Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.
- Purification
- Purified
- Purity
- >95 %
- Grade
- GMP Grade
- Immunogen
- WM245 melanoma cells
- Clone
- ME20-4
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product NGFR Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Alternative Name
- CD271 (NGFR Products)
- Synonyms
- ngfr antibody, wu:fb38c02 antibody, wu:fc10h01 antibody, CD271 antibody, Gp80-LNGFR antibody, TNFRSF16 antibody, p75(NTR) antibody, p75NTR antibody, LNGFR antibody, RNNGFRR antibody, Tnfrsf16 antibody, p75 antibody, NRH1b antibody, fullback antibody, nrh1 antibody, p75ntr antibody, tnfrsf16 antibody, p75NGFR antibody, nerve growth factor receptor antibody, neurotrophin receptor associated death domain antibody, nerve growth factor receptor S homeolog antibody, nerve growth factor receptor (TNFR superfamily, member 16) antibody, NGFR antibody, nradd antibody, Ngfr antibody, ngfr.S antibody
- Background
- The clone ME20.4, a mouse monoclonal antibody selectively binds with a ~75 kD type I transmembrane protein known as CD271. It is also known as the nerve growth factor receptor (NGFR) and a member of the tumor necrosis factor receptor (TNFR) superfamily. Various cell types express CD271 including neuronal axons, Schwann cells, mesenchymal stem cells, epithelial cells, etc. Increased levels of CD271 were observed in brain metastatic melanoma cells and in lung-metastasizing melanoma cells. It is a transmembrane signaling receptor involved in negative cell cycle regulation and is specific for neural crest origin.
- Gene ID
- 4804
- UniProt
- P08138
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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