CD56 antibody
Quick Overview for CD56 antibody (ABIN7077332)
Target
See all CD56 (NCAM1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- CD56 Unconjugated Antibody
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Characteristics
- Clone MY31, a mouse antibody, binds to the human 140- kDa glycoprotein, an isoform of neural cell adhesion molecule (NCAM) known as CD56. CD56 and CD16 expressing lymphocytes are primarily considered as human NK cells and NK-T cells. A subset of CD56+ NK cells play a unique functional role in the innate immune response as the primary source of NK cell-derived immunoregulatory cytokines, regulated in part by differential monokine production. CD56 is also expressed in normal and neoplastic human neuroendocrine tissues, certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias. Increased CD56 + lymphocyte subsets in peripheral blood has a significant predictive or prognostic factor in metastatic breast cancer.
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Purification
- Purified
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Purity
- >95 %
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Immunogen
- KG1a cell line
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Alternative Name
- CD56
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Gene ID
- 4684
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UniProt
- P13591
Target
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