EDNRB antibody (PE-Cy7)

Catalog No. ABIN705129

The PE-Cy7-conjugated Rabbit Polyclonal anti-EDNRB antibody (ABIN705129) specifically detects EDNRB in WB and FACS. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Pig and Chicken samples.

Quick Overview for EDNRB antibody (PE-Cy7) (ABIN705129)

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDNRB antibody is conjugated to PE-Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-EDNRB Antibody (PE-Cy7)

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Endolin B Receptor

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EDNRB

Target: EDNRB (Endothelin Receptor Type B (EDNRB))

Alternative Name: ETBR/Endothelin B Receptor

Background:

Synonyms: ABCDS, Ednra, Ednrb, EDNRB_HUMAN, Endothelin B receptor, Endothelin B receptor precursor, Endothelin receptor Non selective type, Endothelin receptor non-selective type, Endothelin receptor type B, ET B, ET-B, ET-BR, ETB, ETRB, Hirschsprung disease 2, HSCR, HSCR2, EDNRB, HSCR, WS4A.

Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 47kDa

Gene ID: 1910

UniProt: P24530

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process