BCL10 antibody (AA 1-130)

Catalog No. ABIN7090778

The Mouse Monoclonal anti-BCL10 antibody (Clone G56) (ABIN7090778) specifically detects BCL10 in WB, FACS, IHC (p), IF (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for BCL10 antibody (AA 1-130) (ABIN7090778)

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BCL10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: G56

Product Details anti-BCL10 Antibody

Binding Specificity: AA 1-130

Purpose: BCL10 Monoclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human BCL10

Isotype: IgG1 kappa

Application Details

Application Notes: WB(WB(1:500-2000)), FCM(FCM(1:50-100)), IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500)), IF(IHC-P)(IF(IHC-P)(1:100-500))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BCL10

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Alternative Name: BCL10

Background:

Synonyms: Bcl-10, B cell CLL/lymphoma 10, B cell lymphoma/leukemia10, B-cell leukemia/lymphoma 10, Bcl 10, c E10, c-E10, C81403, CARD containing apoptotic signaling protein, CARD containing molecule enhancing NF kappa B, CARD containing molecule enhancing NF kB, CARD containing molecule enhancing NFkB, CARD containing proapoptotic protein, CARD like apoptotic protein, CARMEN, Caspase recruiting domain containing protein, cCARMEN, cE 10, cE10, CED 3/ICH 1 prodomain homologous E10 like regulator, CED3/ICH1 prodomain homologous E10 like regulator, Cellular E10, Cellular homolog of vCARMEN, CIPER, CLAP, hCLAP, Mammalian CARD containing adapter molecule E10, mE 10, mE10, R-RCD1, BCL10_HUMAN.

Background: Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Gene ID: 8915

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins