Recombinant CD2 antibody

Catalog No. ABIN7090867

The Rabbit Monoclonal anti-CD2 antibody is suitable to detect CD2 in samples from Human. It has been validated for IHC (p), IHC (fro) and IF (p).

Quick Overview for Recombinant CD2 antibody (ABIN7090867)

Target: CD2

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CD2 Antibody

Purpose: CD2 Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD2

Isotype: IgG

Application Details

Application Notes: IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500)), IF(IHC-P)(IF(IHC-P)(1:100-500))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CD2

Target: CD2

Alternative Name: CD2

Background:

Synonyms: T-cell surface antigen CD2, CD 2, CD2 antigen, CD2 Molecule, LFA2, LFA3 receptor, Lymphocyte function antigen 2, p50, Rosette receptor, Sheep erythrocyte receptor, Sheep red blood cell receptor, SRBC, T cell surface antigen CD2, T cell surface antigen T11/Leu 5, T11, CD2_HUMAN.

Background: CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95 % of thymocytes, it is also found on some natural killer cells but not on B lymphocytes.
CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.

Gene ID: 914

UniProt: P06729