EPH Receptor A2 antibody

Catalog No. ABIN7091063

This anti-EPH Receptor A2 antibody is a Rabbit Monoclonal antibody detecting EPH Receptor A2 in WB and IHC (p). Suitable for Human.

Quick Overview for EPH Receptor A2 antibody (ABIN7091063)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: E12A2

Product Details anti-EPH Receptor A2 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EphA2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EphA2

Background:

Synonyms: ARCC2, Eck, Eph receptor A2 antibody EphA2, Ephrin receptor, Ephrin receptor EphA2, Ephrin type A receptor 2, Epithelial cell kinase, Epithelial cell receptor protein tyrosine kinase antibody Myk 2, Myk2, Sek 2, Sek2, Tyrosine protein kinase receptor ECK, Tyrosine-protein kinase receptor MPK-5, Tyrosine-protein kinase receptor SEK-2, EPHA2_HUMAN.

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010].

Gene ID: 1969

UniProt: P29317

Pathways: RTK Signaling