EPH Receptor A2 antibody

Catalog No. ABIN7091063

The Rabbit Monoclonal anti-EPH Receptor A2 antibody (Clone E12A2) (ABIN7091063) specifically detects EPH Receptor A2 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for EPH Receptor A2 antibody (ABIN7091063)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: E12A2

Product Details anti-EPH Receptor A2 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EphA2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EphA2

Background:

Synonyms: ARCC2, Eck, Eph receptor A2 antibody EphA2, Ephrin receptor, Ephrin receptor EphA2, Ephrin type A receptor 2, Epithelial cell kinase, Epithelial cell receptor protein tyrosine kinase antibody Myk 2, Myk2, Sek 2, Sek2, Tyrosine protein kinase receptor ECK, Tyrosine-protein kinase receptor MPK-5, Tyrosine-protein kinase receptor SEK-2, EPHA2_HUMAN.

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010].

Gene ID: 1969

UniProt: P29317

Pathways: RTK Signaling