GLS2 antibody

Catalog No. ABIN7091165

This anti-GLS2 antibody is a Mouse Monoclonal antibody detecting GLS2 in WB and IHC (p). Suitable for Human.

Quick Overview for GLS2 antibody (ABIN7091165)

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: Y09A1

Product Details anti-GLS2 Antibody

Predicted Reactivity: Human,Mouse

Immunogen: Recombinant human GLS2.

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GLS2

Target: GLS2 (Glutaminase 2 (Liver, Mitochondrial) (GLS2))

Alternative Name: GLS2

Background:

Synonyms: breast cell glutaminase, GLSL_HUMAN, glutaminase 2 (liver mitochondrial), glutaminase 2, glutaminase GA, glutaminase I, Glutaminase liver isoform, hLGA, L glutaminase, L glutamine amidohydrolase, L-glutaminase, L-glutamine amidohydrolase, LGA, mitochondrial, phosphate activated glutaminase, phosphate-dependent glutaminase.

Background: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.

Gene ID: 27165

UniProt: Q9UI32

Pathways: Dicarboxylic Acid Transport, Warburg Effect