MKNK1 antibody (AA 301-400)

Catalog No. ABIN7091357

The Rabbit Polyclonal anti-MKNK1 antibody (ABIN7091357) specifically detects MKNK1 in IF, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for MKNK1 antibody (AA 301-400) (ABIN7091357)

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MKNK1 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MKNK1 Antibody

Binding Specificity: AA 301-400

Purpose: MNK1 Polyclonal Antibody

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MNK1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for MKNK1

Target: MKNK1 (MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1))

Alternative Name: MNK1

Background:

Synonyms: MAP kinase interacting kinase 1, MAP kinase interacting serine/threonine kinase 1, MAP kinase signal integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine-protein kinase 1, MAPK signal integrating kinase 1, MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1, MKNK1, MKNK1_HUMAN, MNK 1, Mnk1.

Background: May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.

Gene ID: 8569

UniProt: Q9BUB5

Pathways: MAPK Signaling, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor