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MME antibody (AA 401-550)

MME Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal B4S1 unconjugated

Catalog No. ABIN7091386

Datasheet as PDF

Target See all MME Antibodies

MME (Membrane Metallo-Endopeptidase (MME))
Binding Specificity
16

14

9

8

8

7

7

7

6

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 401-550
Reactivity
200

57

50

3

2

2

2

2

2

1

1

1

1
Human
Host
109

96

2
Mouse
Compatible Secondaries
Clonality
105

101

2
Monoclonal
Conjugate
103

19

17

13

9

6

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
Application
130

92

78

67

35

27

20

19

13

13

10

8

5

5

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity

Human

Immunogen

KLH conjugated synthetic peptide derived from human CD10

Clone

B4S1

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anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
MME Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 7D4B1 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
MME Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
MME Reactivity: Human, Mouse, Rat FACS, WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal MME-1870 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
MME Reactivity: Human FACS Host: Mouse Monoclonal MEM-78 FITC

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME Reactivity: Human WB, IHC, ELISA, StM, Coat Host: Mouse Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

Application Notes

WB 1:300-5000
IHC-P 1:200-400

Restrictions

For Research Use only
Concentration

0.5 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date

12 months
Target

MME (Membrane Metallo-Endopeptidase (MME))

Alternative Name

CD10 (MME Products)

Synonyms

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

Background

Synonyms: MME, NEP, NEP_HUMAN, Atriopeptidase, CALLA, CD 10, CD10, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24.11, Enkephalinase, EPN, gp100, Membrane metallo endopeptidase, Membrane metalloendopeptidase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10, Membrane metalloendopeptidase variant 1, Membrane metalloendopeptidase variant 2, MGC126681, MGC126707, Neprilysin, Neutral endopeptidase 24.11, Neutral endopeptidase, Neprilysin, Skin fibroblast elastase, SFE.
Background: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.

Gene ID

4311

UniProt

P08473

Pathways

RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration