Mesothelin antibody

Catalog No. ABIN7091402

The Rabbit Monoclonal anti-Mesothelin antibody (Clone H5A8) (ABIN7091402) specifically detects Mesothelin in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Mesothelin antibody (ABIN7091402)

Target: Mesothelin (MSLN)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Mesothelin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: H5A8

Product Details anti-Mesothelin Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Mesothelin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Mesothelin

Target: Mesothelin (MSLN)

Alternative Name: Mesothelin

Background:

Synonyms: MSLN, MES, CAK 1, CAK1, CAK1 antigen, Megakaryocyte potentiating factor, Mesothelin isoform 1 precursor, MPF, Pre pro megakaryocyte potentiating factor, SMR, SMRP, Soluble MPF mesothelin related protein, MSLN_HUMAN.

Background: Mesothelin(MSLN)may play a role in cell adhesion and cell shape dynamics, human homolog highly expressed in renal cell carcinoma. malignant tumors, such as a skin lump, ovary cancer and the pancreas cancer...etc..Mainly used for the research of the malignant tumor.

Gene ID: 10232

UniProt: Q13421

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process