PIN1 antibody
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- Target See all PIN1 Antibodies
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PIN1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Predicted Reactivity
- Human,Mouse,Cow
- Immunogen
- Recombinant human UBL5 (Fragment) (His-tagged).
- Clone
- F12S3
- Isotype
- IgG1
- Top Product
- Discover our top product PIN1 Primary Antibody
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- Application Notes
- WB 1:300-5000
- Restrictions
- For Research Use only
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- Concentration
- 0.5 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
- Alternative Name
- PIN1 (PIN1 Products)
- Synonyms
- DOD antibody, UBL5 antibody, dod antibody, ubl5 antibody, pin1 antibody, pin1a antibody, 0610025L01Rik antibody, D9Bwg1161e antibody, pin1b antibody, zgc:73206 antibody, PPIase pin1 antibody, MdPin1 antibody, Pin1 antibody, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 antibody, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog antibody, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 antibody, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog antibody, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody, peptidyl-prolyl cis-trans isomerase Pin1 antibody, PIN1 antibody, Pin1 antibody, pin1 antibody, pin1.S antibody, pin1.L antibody, ppiD antibody, PITG_11123 antibody, LOC103419188 antibody
- Background
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Synonyms: DOD, NIMA interacting 1, Peptidyl prolyl cis trans isomerase NIMA interacting 1, Peptidyl prolyl cis/trans isomerase NIMA interacting, Pin 1, PPIase Pin1, Prolyl isomerase, Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1, Protein NIMA interacting 1, Rotamase Pin1, UBL 5, UBL5, PIN1_HUMAN.
Background: Essential PPIase that regulates mitosis presumably byinteracting with NIMA and attenuating its mitosis-promotingactivity. Displays a preference for an acidic residue N-terminal tothe isomerized proline bond. Catalyzes pSer/Thr-Pro cis/transisomerizations. Down-regulates kinase activity of BTK. Cantransactivate multiple oncogenes and induce centrosomeamplification, chromosome instability and cell transformation.Required for the efficient dephosphorylation and recycling of RAF1after mitogen activation.
- Gene ID
- 5300
- UniProt
- Q13526
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