Recombinant P-Selectin antibody

Catalog No. ABIN7091681

The Rabbit Monoclonal anti-P-Selectin antibody (ABIN7091681) specifically detects P-Selectin in IHC (fro), IHC (p) and IF (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant P-Selectin antibody (ABIN7091681)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This P-Selectin antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-P-Selectin Antibody

Purpose: CD62p Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD62p

Isotype: IgG, kappa

Application Details

Application Notes: IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500)), IF(IHC-P)(IF(IHC-P)(1:100-500))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62p

Background:

Synonyms: CD62P Rabbit mAb, P-selectin, CD_antigen: CD62P, CD62 antigen-like family member P, GMP 140, GMP-140, GMRP, Granule membrane protein 140, Granulocyte membrane protein, GRMP, LECAM 3, LECAM3, Leukocyte endothelial cell adhesion molecule 3, Leukocyte-endothelial cell adhesion molecule 3, P Selectin, PADGEM, Platelet activation dependent granule-external membrane protein, PSEL, sp-selectin, LYAM3_HUMAN.

Background: This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]

Gene ID: 6403

UniProt: Q01102