CD80 antibody (AA 35-242)

Catalog No. ABIN7092910

The Rabbit Monoclonal anti-CD80 antibody has been validated for FACS and ELISA. It is suitable to detect CD80 in samples from Human.

Quick Overview for CD80 antibody (AA 35-242) (ABIN7092910)

Target: CD80

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: DM109

Product Details anti-CD80 Antibody

Binding Specificity: AA 35-242

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human B7-1 (Val35-Asn242) (ABIN6961158) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1/5000-10000,Flow Cyt  1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: B7-1

Background: Synonyms:CD80,B7,B7-1,B7.1,BB1,CD28LG,CD28LG1,LAB7
Description:The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

Molecular Weight: 50.0 kDa

Gene ID: 941

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints