CD25 antibody (AA 22-213)

Catalog No. ABIN7092948

This Rabbit Monoclonal antibody specifically detects CD25 in FACS and ELISA. It exhibits reactivity toward Human.

Quick Overview for CD25 antibody (AA 22-213) (ABIN7092948)

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD25 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: DM148

Product Details anti-CD25 Antibody

Binding Specificity: AA 22-213

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human IL2RA(Glu22-Cys213) (ABIN6964077) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1/5000-10000,Flow Cyt 1/100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CD25

Target: CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Alternative Name: IL2RA

Background: Synonyms:IL2RA,CD25,p55,IL2-RA,IL-2-RA
Description:The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Molecular Weight: 30.8KDa

Pathways: JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation