CXCL13 antibody (AA 23-109)

Catalog No. ABIN706691

There are 3+ publications for this product available. The Rabbit Polyclonal anti-CXCL13 antibody is suitable to detect CXCL13 in samples from Human. It has been validated for WB, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for CXCL13 antibody (AA 23-109) (ABIN706691)

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCL13 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CXCL13 Antibody

Binding Specificity: AA 23-109

Purpose: CXCL13/BCA1 Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CXCL13/BCA1

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CXCL13 antibody (ABIN706691)

Doloff, Veiseh, Vegas, Tam, Farah, Ma, Li, Bader, Chiu, Sadraei, Aresta-Dasilva, Griffin, Jhunjhunwala, Webber, Siebert, Tang, Chen, Langan, Dholokia, Thakrar, Qi, Oberholzer, Greiner, Langer et al.: "Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. ..." in: Nature materials, Vol. 16, Issue 6, pp. 671-680, (2017) (PubMed).

Wang, Cao, Li, Zhang: "Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection." in: Cytokine, Vol. 88, pp. 232-240, (2016) (PubMed).

Siepert, Brösel, Vogt, Ahrlich, Schmitt-Knosalla, Loddenkemper, Kühl, Baumgrass, Gerstmayer, Tomiuk, Tiedge, Viklický, Brabcova, Nizze, Lehmann, Volk, Sawitzki: "Mechanisms and Rescue Strategies of Calcineurin Inhibitor Mediated Tolerance Abrogation Induced by Anti-CD4 mAb Treatment." in: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, (2013) (PubMed).

Target Details for CXCL13

Target: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Alternative Name: CXCL13/BCA1

Background:

Synonyms: BLC, Angie, BCA-1, BLR1L, ANGIE2, Scyb13, 4631412M8Rik, C-X-C motif chemokine 13, B lymphocyte chemoattractant, CXC chemokine BLC, Small-inducible cytokine B13, Cxcl13

Background: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Gene ID: 10563

UniProt: O43927