ACCN1 antibody

Catalog No. ABIN7111514

The Rabbit Polyclonal anti-ACCN1 antibody is suitable to detect ACCN1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for ACCN1 antibody (ABIN7111514)

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACCN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ACCN1 Antibody

Purpose: ASIC2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: amiloride-sensitive cation channel 1, neuronal

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ACCN1

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Alternative Name: ASIC2

Background:

Synonyms: Acid-sensing ion channel 2 (ASIC2)|Amiloride-sensitive brain sodium channel|Amiloride-sensitive cation channel 1, neuronal|Amiloride-sensitive cation channel neuronal 1|Brain sodium channel 1 (BNC1, BNaC1)|Mammalian degenerin homolog (MDEG)|ASIC2|ACCN|ACCN1|BNAC1|MDEG

Background: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.

Molecular Weight: 70 kDa

Gene ID: 40

UniProt: Q16515

Pathways: Sensory Perception of Sound