BHLHA15 antibody

Catalog No. ABIN7111941

This anti-BHLHA15 antibody is a Rabbit Polyclonal antibody detecting BHLHA15 in ELISA, WB and IP. Suitable for Human, Mouse and Rat.

Quick Overview for BHLHA15 antibody (ABIN7111941)

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHA15 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-BHLHA15 Antibody

Purpose: BHLHA15 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: basic helix-loop-helix family, member a15

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BHLHA15

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Alternative Name: BHLHA15

Background:

Synonyms: Class A basic helix-loop-helix protein 15 (bHLHa15)|Class B basic helix-loop-helix protein 8 (bHLHb8)|Muscle, intestine and stomach expression 1 (MIST-1)|BHLHA15|BHLHB8|MIST1

Background: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity).

Molecular Weight: 30 kDa

Gene ID: 168620

UniProt: Q7RTS1