BHLHA15 antibody (AA 2-72) (Biotin)

Catalog No. ABIN7147830

Product Details anti-BHLHA15 Antibody (Biotin)

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Binding Specificity: AA 2-72

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHA15 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BHLHA15

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Alternative Name: BHLHA15 (BHLHA15 Products)

Synonyms: BHLHB8 antibody, MIST1 antibody, 1810009C13Rik antibody, Bhlhb8 antibody, MIST-1 antibody, Mist1 antibody, bHlH antibody, basic helix-loop-helix family member a15 antibody, basic helix-loop-helix family, member a15 antibody, BHLHA15 antibody, Bhlha15 antibody

Background:

Background: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5\'-CANNTG-3\' (By similarity).

Aliases: Basic helix loop helix domain containing class B 8 antibody, Basic helix loop helix family member a15 antibody, BHA15_HUMAN antibody, Bhlha15 antibody, bHLHB8 antibody, Class A basic helix-loop-helix protein 15 antibody, Class B basic helix-loop-helix protein 8 antibody, Class II bHLH protein MIST1 antibody, intestine and stomach expression 1 antibody, MIST 1 antibody, MIST-1 antibody, MIST1 antibody, Muscle antibody, Muscle intestine and stomach expression 1 antibody, protein MIST1 antibody

UniProt: Q7RTS1