BID antibody (AA 1-195)

Catalog No. ABIN7112003

The Mouse Monoclonal anti-BID antibody has been validated for WB and ELISA. It is suitable to detect BID in samples from Human.

Quick Overview for BID antibody (AA 1-195) (ABIN7112003)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BID antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6E8

Product Details anti-BID Antibody

Binding Specificity: AA 1-195

Purpose: BID antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-195aa

Immunogen: BH3 interacting domain death agonist

Isotype: IgG2a

Application Details

Application Notes: WB: 1:2000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BID

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Alternative Name: BID

Background:

Synonyms: BH3-interacting domain death agonist|p22 BID (BID)|BH3-interacting domain death agonist p15 Alternative names: p15 BID|BH3-interacting domain death agonist p13 Alternative names: p13 BID|BH3-interacting domain death agonist p11 Alternative names: p11 BID|BID

Background: The major proteolytic product p15 BID allows the release of cytochrome c(By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

Molecular Weight: 22 kDa

Gene ID: 637

UniProt: P55957

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity