CES1 antibody

Catalog No. ABIN7112300

Product Details anti-CES1 Antibody

Target: CES1 (Carboxylesterase 1 (CES1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: CES1 (CES1 Products)

Synonyms: ACAT antibody, CE-1 antibody, CEH antibody, CES2 antibody, HMSE antibody, HMSE1 antibody, PCE-1 antibody, REH antibody, SES1 antibody, TGH antibody, hCE-1 antibody, CESDD1 antibody, CES1 antibody, CES-K1 antibody, APLE antibody, PMPMEase antibody, CES antibody, carboxylesterase 1 antibody, liver carboxylesterase 1 antibody, liver carboxylesterase antibody, carboxylesterase 1 (monocyte/macrophage serine esterase 1) antibody, CES1 antibody, CpipJ_CPIJ013026 antibody, CpipJ_CPIJ016339 antibody, LOC100009551 antibody, LOC454097 antibody, LOC699486 antibody, LOC100050915 antibody

Background: Synonyms:CES2, SES1 Background:This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Molecular Weight: 62 kDa

Gene ID: 1066

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process