CD80 antibody

Catalog No. ABIN7112518

This Mouse Monoclonal antibody specifically detects CD80 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD80 antibody (ABIN7112518)

Target: CD80

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD80 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4H6

Product Details anti-CD80 Antibody

Purpose: CD80 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: CD80

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000-1:4000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CD80

Target: CD80

Alternative Name: CD80

Background:

Synonyms: T-lymphocyte activation antigen CD80|Activation B7-1 antigen|BB1|CTLA-4 counter-receptor B7.1 (B7)|CD80|CD28LG|CD28LG1|LAB7

Background: Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.

Molecular Weight: 60 kDa

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints