CDCA8 antibody

Catalog No. ABIN7112582

The Rabbit Polyclonal anti-CDCA8 antibody has been validated for WB, IHC and ELISA. It is suitable to detect CDCA8 in samples from Human, Mouse and Rat.

Quick Overview for CDCA8 antibody (ABIN7112582)

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCA8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CDCA8 Antibody

Purpose: CDCA8 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: cell division cycle associated 8

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Alternative Name: CDCA8

Background:

Synonyms: Borealin|Cell division cycle-associated protein 8|Dasra-B (hDasra-B)|Pluripotent embryonic stem cell-related gene 3 protein|CDCA8|PESCRG3

Background: Component of the chromosomal passenger complex(CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Molecular Weight: 38-40 kDa

Gene ID: 55143

UniProt: Q53HL2

Pathways: Cell Division Cycle, M Phase