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CC2D1A antibody

CC2D1A Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7112928
  • Target See all CC2D1A Antibodies
    CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
    Reactivity
    Human, Mouse, Rat
    Host
    • 32
    • 2
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CC2D1A antibody is un-conjugated
    Application
    • 25
    • 14
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    coiled-coil and C2 domain containing 1A
    Isotype
    IgG
    Top Product
    Discover our top product CC2D1A Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))
    Alternative Name
    CC2D1A (CC2D1A Products)
    Synonyms
    mrt3 antibody, freud-1 antibody, FREUD-1 antibody, Freud-1/Aki1 antibody, MRT3 antibody, BC016188 antibody, Freud-1 antibody, Tape antibody, RGD1306108 antibody, coiled-coil and C2 domain containing 1A antibody, CC2D1A antibody, cc2d1a antibody, Cc2d1a antibody
    Background
    Synonyms:AKI1 Background:Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.
    Molecular Weight
    130 kDa, 104 kDa
    Gene ID
    54862
    UniProt
    Q6P1N0
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