Crossover junction endonuclease EME1 (EME1) antibody

Catalog No. ABIN7113082

This Rabbit Polyclonal antibody specifically detects Crossover junction endonuclease EME1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Crossover junction endonuclease EME1 (EME1) antibody (ABIN7113082)

Target: Crossover junction endonuclease EME1 (EME1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Purpose: EME1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: essential meiotic endonuclease 1 homolog 1(S. pombe)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details

Target: Crossover junction endonuclease EME1 (EME1)

Alternative Name: EME1

Background:

Synonyms: Crossover junction endonuclease EME1|MMS4 homolog (hMMS4)|EME1|MMS4

Background: Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

Molecular Weight: 65 kDa

Gene ID: 146956

UniProt: Q96AY2