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Crossover junction endonuclease EME1 (EME1) (Internal Region) antibody

EME1 Reactivity: Human WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6256869
  • Target See all Crossover junction endonuclease EME1 (EME1) Antibodies
    Crossover junction endonuclease EME1 (EME1)
    Binding Specificity
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 19
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 16
    • 4
    Rabbit
    Clonality
    • 18
    • 2
    Polyclonal
    Conjugate
    • 16
    • 2
    • 1
    • 1
    Un-conjugated
    Application
    • 15
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    EME1 Antibody detects endogenous levels of total EME1.
    Predicted Reactivity
    Rabbit,Dog
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human EME1, corresponding to a region within the internal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product EME1 Primary Antibody
  • Application Notes
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Crossover junction endonuclease EME1 (EME1)
    Alternative Name
    EME1 (EME1 Products)
    Synonyms
    6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody
    Background

    Description: Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

    Gene: EME1

    Molecular Weight
    65 kDa
    Gene ID
    146956
    UniProt
    Q96AY2
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